Platelet-rich Plasma (PRP)

Image-guided platelet-rich plasma for spinal pain, joints, tendons, ligaments,
pulmonary applications and selected experimental applications.

Why PRP Starts With Diagnosis

PRP is only as good as the diagnosis, the dose and the delivery.

Platelet-rich plasma, or PRP, is a regenerative treatment made from your own blood and used in selected musculoskeletal, neurological, gynecological and pulmonary conditions to support repair, modulate inflammation and improve function. At MBR Health on the Gold Coast, PRP is used for carefully selected cases of osteoarthritis, tendon injury, ligament injury, muscle injury, pulmonary issues and some nerve-related pain pathways.

But PRP is not a generic product. The quality of a PRP treatment depends on the platelet dose, the cellular composition, the way it is prepared, and whether it is delivered accurately to the tissue actually driving the problem. That is why PRP at MBR Health is selected only after diagnosis has been defined and the biological target is clear.

If you have ever had PRP that did not work, please see “Why my PRP didn’t work” and for further information please see:

US-guided Platelet-rich Plasma Knee Injection

What Makes PRP Clinically Meaningful

Not all PRP delivers the same result. The outcome depends on what is delivered, where it is placed and whether the biology suits the tissue. Five key factors determine whether treatment is likely to work.

Platelet Dose

PRP is not simply “spun blood.” The number of platelets delivered matters, because platelets carry many of the signalling molecules that drive the biological response. Recent reviews suggest clinical outcomes in some musculoskeletal applications, particularly knee osteoarthritis, may improve when a more meaningful platelet dose is delivered rather than a very low-dose preparation.

Accuracy of Delivery

PRP only works at the tissue it reaches. A joint surface, tendon origin, partial tear, ligament insertion, enthesis and nerve-adjacent plane are not the same target. If the biologic is not placed accurately, the treatment may underperform even when the PRP itself is good. That is why delivery should be selected according to the anatomy and performed under imaging guidance where appropriate.

Platelet Quality

You are the pharmacy for this treatment. PRP is made from your own blood, so the functional quality of your platelets matters, not just the count. Some medications — particularly non-selective NSAIDs and antiplatelet drugs — can impair platelet activation or growth factor release, which may reduce the biological quality of the final PRP product. This is one reason pre-procedure preparation matters.

Processing Technique

How PRP is prepared can influence what is ultimately delivered. Important variables include the preparation method, centrifugation protocol, sterility pathway, anticoagulant choice, time from collection to injection, and which cellular and plasma fractions are preserved or discarded. These details can affect platelet recovery, activation behaviour and the growth factor profile of the final product. A closed, well-controlled preparation pathway helps support product quality and procedural safety.

Adjunct Therapies

Adjunctive strategies may sometimes be discussed to support recovery after PRP, but they should be presented carefully. Rehabilitation, load modification and tissue-specific physiotherapy remain the most established adjuncts. Hyperbaric oxygen therapy has some emerging musculoskeletal literature, but the overall evidence remains limited and protocols are not standardised. Peptide-based adjuncts are even less established for musculoskeletal PRP pathways, and in Australia many peptide products are regulated as therapeutic goods, with recent TGA warnings about unapproved peptide products and their safety. Any discussion of adjuncts should therefore be selective, evidence-aware and clinically individualised.

Who May Benefit

Platelet-rich Plasma may be considered for:

Disclaimer

The information on this page is intended as general health information only and does not constitute medical advice. Platelet-rich plasma therapy at MBR Health is performed following referral from a treating GP or specialist, with suitability determined on an individual basis. All procedures carry potential risks and benefits that will be discussed prior to treatment as part of the informed consent process. Some applications of PRP listed on this page — including pulmonary applications — are investigational in nature, based on emerging case study evidence and not yet supported by established clinical guidelines for routine therapeutic use.

Patients interested in investigational applications are encouraged to discuss individual suitability with their treating clinician. MBR Health does not guarantee specific clinical outcomes from PRP therapy. Results vary depending on individual patient factors, the nature of the condition and the specific application performed.

  • Osteoarthritis
  • Tendon Injury
  • Ligament Injury
  • Muscle Injury
  • Spine-related Pain
  • Nerve-related Pain
  • Pulmonary Applications
  • Evolving Research-based Applications

“The question is not simply whether PRP is being injected. The question is whether the platelet dose is meaningful, whether the PRP composition is optimised, whether the biology suits the tissue, and whether the delivery is reaching the structure that actually needs treatment.”

Dr Zane Sherif, specialist Radiologist

How Our PRP Pathway Works

From assessment
to delivery.

01.

Assessment & imaging

PRP is not selected because it sounds advanced. It is selected because the diagnosis, tissue type and clinical objective support a biologic treatment pathway.

02.

Blood Collection & Preparation

PRP is created from your own blood using a high-volume, closed preparation system designed to produce a clinically meaningful platelet concentrate while maintaining sterility and procedural control. Pre-procedure preparation matters — patients may be asked to avoid smoking, alcohol and anti-inflammatory medications before treatment. For further details, please refer to our Pre-PRP Preparation Guide.

03.

Image-guided PRP Delivery

PRP is delivered to the tissue actually being treated - not just the general area of pain. Depending on the anatomy and clinical goal, this may involve ultrasound guidance, CT guidance or a combined imaging strategy.

04.

Recovery & Follow-Up

Recovery after a PRP injection varies according to the condition treated, the tissue involved and the extent of the underlying injury. Some patients experience a temporary increase in pain, stiffness or swelling as the early biological response develops, while improvement may occur gradually over several weeks or months. Patients receive individualised advice regarding activity modification, rehabilitation and the appropriate timing of return to exercise. Clinical follow-up allows the response to PRP treatment to be assessed and the recovery plan adjusted where necessary. In selected cases, follow-up MRI or ultrasound may also be used to evaluate structural healing and guide further treatment.

Clinical Suitability US-guided PRP KNEE Injection

Clinical Suitability

Not every pain needs PRP. Not every injection is regenerative.

PRP is not suitable for every patient, every tissue or every pain pattern. Suitability depends on diagnosis, imaging findings, medical history, tissue viability, alternative treatment options and the evidence available for the condition being treated.

This is one of the reasons PRP should sit inside a diagnosis-led medical pathway rather than being offered as a standalone trend treatment.

Common Questions from Patients

Frequently Asked Questions

What is PRP?

PRP stands for platelet-rich plasma. It is a treatment made from your own blood, processed to concentrate platelets and their associated signalling molecules, then delivered to a selected tissue target.

Is all PRP the same?

No. PRP can vary significantly depending on platelet dose, cellular composition, how it is prepared and how it is delivered. That is why two clinics may both say they offer PRP while delivering very different products.

What is PRP used for?

PRP may be used in selected cases of osteoarthritis, tendinopathy, ligament injury, muscle injury and some nerve-related or spine-adjacent pain pathways where the diagnosis and tissue target support a biologic treatment rationale.

How is PRP different from cortisone?

Cortisone is generally used to suppress inflammation and can provide faster short-term symptom relief. PRP is a biologic treatment intended to stimulate a healing response and is not designed as an immediate anaesthetic or steroid-like effect.

Why does platelet dose matter in PRP?

Platelet dose matters because platelets carry growth factors and other signalling molecules that influence the tissue response. A higher-quality PRP pathway aims to deliver a clinically meaningful platelet concentrate rather than a minimal or highly diluted preparation.

Is PRP image-guided?

At MBR Health, PRP is image-guided where appropriate so the biologic is delivered to the tissue actually being treated rather than the general area of pain. Guidance may involve ultrasound, CT or another imaging strategy depending on the anatomy.

How much blood is needed for PRP?

This depends on the system being used, the platelet dose required and the tissue being treated. Higher-dose PRP pathways usually require a larger blood draw than simplified tube-based systems.

Is PRP safe?

Because PRP is made from your own blood, it avoids the issues associated with donor tissue or foreign biologics. However, procedural safety still depends on appropriate patient selection, sterile preparation, imaging guidance and medical governance.

How long does PRP take to work?

PRP is not designed to work like a steroid injection. Some patients notice improvement within weeks, while others require longer depending on the tissue, chronicity and biological response.

Is PRP Covered by Medicare?

Platelet-rich plasma therapy is not currently covered by Medicare in Australia. PRP is considered an emerging and investigational therapy for most indications and does not attract a Medicare rebate.

All PRP procedures at MBR Health are privately
billed Why choose MBR Health for PRP?

MBR Health’s PRP pathway is built around diagnosis, biologic quality and precision delivery. The aim is not simply to offer PRP, but to decide when it is appropriate, prepare it properly and deliver it to the right target.

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Take the next step

Speak to your doctor.

If you are considering PRP, speak to your doctor about if platelet-rich plasma is the right biologic pathway for your condition.
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